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Although some studies have demonstrated benefits such as increased lean body mass and improved body composition (in populations with clinical need for the drugs), these gains have not consistently translated into enhancements in muscle strength, physical performance, or overall quality of life

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Follow-up testing should occur at 8 to 12-week intervals to titrate the dosage appropriately and ensure that IGF-1 levels remain within the optimal, age-adjusted upper quartile without inducing hyperinsulinemia

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