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Lastly, people with very severe ME/CFS are bedbound (11) and have a functional capacity of less than 5% (39)

Moreover, MenSCs promoted the transformation of microglia into a neuroprotective phenotype, facilitating anti-inflammatory cytokine secretion and markedly improving cognitive deficits in APP/PS1 transgenic mice

Finally, we highlight the remaining challenges for NADs development, offering references for the design and clinical application of novel NADs

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In fact, at GSH concentrations within the physiological range in red blood cells, SNO-Hb can still promote vasodilation even under oxygenated conditions (46)