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Aptamers against cells overexpressing glypican 3 from expanded genetic systems combined with cell engineering and laboratory evolution

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Only the holoTC complex can be taken up by cells and used for biological processes such as methylation

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Gating residues involved in the occluded-to-inward conformational transition of OCTN2 Alternating-access transport by secondary active transporters requires the coordination of gates that enclose or preclude access to the substrate-binding site from either side of the membrane 51