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Strategies to minimize discomfort Follow the titration schedule The single most effective strategy is respecting the four-week intervals between dose increases

For each MS-DRG, compute the median [501] of the MAO payer-specific negotiated charge in the list from Step 3

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[4] [3] Without adequate B12, nerve signals cannot transmit efficiently, potentially leading to neurological symptoms such as tingling, numbness, or balance problems

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