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MD-LGBM achieved the best results for CITRUS (AUROC = 0.883

Food Chem 131:754760

Such discrepancies point out to possible missing links in the metabolic pathways based on the current status of the gene sequencing and annotations

ER seems to be the predominant receptor subtype in the brain, although there are some differences in expression of each receptor between the sexes and between ovariectomized female animals and those treated with estrogen (Vanderhorst et al., 2005)