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Neoadjuvant atezolizumab demonstrated a pCR benefit when added to an anthracycline-free regimen of carboplatin and paclitaxel in a phase II trial of 67 patients [72]

CJC-1295 with DAC has a half-life of several days, allowing once or twice-weekly dosing, while CJC-1295 no DAC has a 30-minute half-life requiring 23 daily doses