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The vascular system beneath the gastric mucosa promptly reacts to a significant surge in mucosal blood flow when exposed to aggressive luminal factors, a process mediated by sensory afferent nerves [77]

For intracellular cytokine, staining cells were fixed with BD Cytofix Cytoperm (BD Biosciences) for 20 min at 4 C, washed twice with 1x saponin buffer (0.5% (w/v) saponin [Carl Roth], 2 mM EDTA, 2% FCS, in PBS) and stained for IFN (see Table 1) overnight at 4 C in 1 saponin buffer

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In particular, carrier family 38 member 1 (SLC38A1)- and SLC1A5-mediated l-glutamine (but not d-glutamine) uptake and subsequent glutaminase 2 (GLS2, but not GLS1)-mediated glutamate production is required for cystine deprivation- or erastin-induced ferroptosis 40 (Fig