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Treatment options can include: Supplements Oral B12 : Effective for most people, even those with mild malabsorption Sublingual B12 : Dissolves under the tongue, dominantly orally with some absorption passing into the bloodsteam Injectable B12: Used in specific cases, for example if someone is not responding to oral or sublingual supplements

One of these conditions is specifically tied to B12 deficiency and is known as pernicious anemia

These include TNF-alpha, IL-1 beta, and IL-6, all of which drive joint destruction in inflammatory arthritis

Always mix by gently swirling the vial or rolling it between your hands

Sterile water also has a shorter shelf life after opening