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Radioembolization plus chemotherapy for first-line treatment of locally advanced intrahepatic cholangiocarcinoma: a phase 2 clinical trial

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10.1016/j.cell.2019.09.001 63 MaF.WuT.ZhaoJ.JiL.SongA.ZhangM.et al

Tumor cells can rapidly develop defenses through metabolic rewiring (e.g., enhanced glycolysis, upregulation of alternative antioxidant pathways), increased expression of metal-efflux pumps (e.g., ATP7A/B), or activation of compensatory survival signals (e.g., Nrf2, FSP1)

Perform the third medication check of the six rights of medication administration at the patients bedside