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Protective effects of swertiamarin against methylglyoxal-induced epithelial-mesenchymal transition by improving oxidative stress in rat kidney epithelial (NRK-52E) cells

In further embodiments, the invention encompasses a method of modulating stem cell differentiation by contacting a stem cell expressing NNMT with one or more cations of the invention and with one or more cations chosen from Tables 3a and 3b

In cases of trauma or illness, such systems communicate through multiple signaling molecules, most of which are also associated with inflammatory and remodeling processes