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The pathophysiology of ALS is still unknown, but altered protein homeostasis has been suggested to be a key player (Wijesekera and Leigh 2009)

Clinicians guide to using ozanimod for the treatment of ulcerative colitis

The Mayo Clinic notes that even at therapeutic mega-doses, side effects are uncommon and mild: headache, nausea, diarrhea, fatigue, and a tingling sensation in extremities