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The suicide modification during catalysis cycle has been reported for oxidoreductases which harbor susceptible amino acids including methionine, cysteine, tryptophan, phenylalanine, tyrosine, and histidine [17]

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However, many candidates met other criteria for eligibility: 53.2% had a history of psoriasis affecting high-impact sites, and 55.2% reported prior but not current use of topical therapy [28]

Pro: Limited studies have suggested that it's more effective than other methods, other than IV, with fewer side effects

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