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Lentiviruses were aliquoted and frozen for further usage

TABLE 3 Comparisons of OCM-related genotypes frequencies between ABLF and NLF groups

Nature, 170(4331), 755

Beyond the observed increase in female lifespan, we show that pharmacologic blockade of IGF-1R signaling preserves, to various degrees, many aspects of healthspan, including neuromuscular function and endurance, and attenuates the age-related increase in diastolic dysfunction, systemic inflammation, and neoplasias in females