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Statements Author contributions All authors listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication

Notably, the administration of cisplatin and paclitaxel can enhance the secretion of exosomal miR-522 by activating the USP7/hnRNPA1 axis in CAFs

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Our data show that MRPL16 , a protein-coding gene that plays a role in mitochondrial translation and PMAIP1 , a protein that promotes activation of caspases and is implicated in mitochondrial damage and apoptosis, are upregulated in AMD RPE