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Weaker labeling of other cytoplasmic areas in these neurons is also present (shown by white asterisks), but some cytoplasmic regions were void of GPX4 immunoreactivity and appeared as empty space (black asterisks)

Meanwhile, MDA, serves as an oxidative stress marker, has been proven to increase in kidneys after hepatic I/R injury 18

One half was fixed in 10% neutral-buffered formalin, processed, and embedded in paraffin

In this regard, natural bioactive components offer a unique advantage due to their pleiotropic effects (109, 110)