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Those with diabetes, pernicious anemia and other diseases may benefit from methylcobalamin supplementation

Deficiency is common in those with fatigue, brain fog, or nutrient absorption issues, especially individuals with gastrointestinal conditions, vegans and vegetarians, or those taking medications like metformin or proton-pump inhibitors

Patel P, Makwana S, Jobanputra U et al (2011) Sublingual route for the systemic delivery of ondansetron

This is particularly beneficial for individuals who suffer from gastrointestinal issues that cause them to have difficulty absorbing food nutrients

In some embodiments, the invention encompasses a method of providing muscular therapy by administering a cation of Formula I, wherein: R 1 is C 1-4 alkyl