glutathione peroxidase ppt Phospholipid Hydroperoxide - an overview Glutathione Peroxidase-1 in Health and

Cancer cells produce significantly higher amounts of ROS than normal cells and therefore administration of prooxidant agents capable of further increase of ROS may represent a potential anticancer approach

Ex vivo , GSSG concentration can increase due to continued reduction of hydrogen peroxide by glutathione peroxidase and reaction with other reactive species

In addition, it has been described that oxidized cardiolipin modulates the biophysical properties of OMM to allow oligomerized Bax to insert and permeabilize the OMM (Mari et al., 2008

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Model and physiological GSSR substrates are, for example, l-cysteine-glutathione disulfide (GSSCys) 9,10,11,12,13,14,15 , coenzyme A-glutathione disulfide 3,16 , as well as S -glutathionylated serum albumin 9,11,17,18,19,20 , sirtuin 21 , sulfiredoxin 22 , and peroxiredoxins 23,24,25,26,27,28,29