melanotic neuroectodermal tumor of infancy chemotherapy Figure 1 from tumour infancy: a case report and review of the aetiopathogenic hypotheses Melanotic Neuroectodermal Tumor of Infancy:

(Baltimora, MA: Johns Hopkins University)

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The variants have both N- and C-terminal nuclear localisation signals (NLSs), but 18 kDa FGF-2 has only C-terminal NLS, and translocation of FGF-2 into the nucleus requires both NLSs, which means transportation of the splicing variants, but not 18 kDa FGF-2, into the nucleus (42)

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Mazur T, Malik M, Bieko DC

Simultaneous GLP-1, GIP, and glucagon receptor activity may help clarify how endocrine pathways coordinate metabolic responses