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The tapering process frequently used in medical detox may help dampen this rebound effect

Steinherz PG, Redner A, Haimi J, Meyers P, Andreeff M

From there, the active ingredients circulate everywhere

NADH:ubiquinone oxidoreductase Complex I catalyzes the two-electron oxidation of NADH and reduction of ubiquinone to ubiquinol which is coupled to the translocation of ~4 H + to the P-side of the MIM (Verkhovskaya and Bloch, 2013)