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A high-fiber diet has been linked to alterations in GIT motility and transit times, which can impact drug distribution and absorption in the GIT

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Edworthy SM, Martin L, Barr SG, Birdsell DC, Brant RF, & Fritzler MJ (1998) A clinical study of the relationship between silicone breast implants and connective tissue disease

However, during physical exertion, hypoxia in myocardial cells leads to incomplete mitochondrial fatty acid oxidation and the accumulation of acyl-carnitines, which can cause cellular membrane degradation

Understanding this distinction matters because more potent does not automatically mean more effective for a given patient