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(A-B) sva algorithm was used to remove batch effect of GSE33118 and GSE26440 datasets, and principal component analysis (PCA) was used to show the original data distribution pattern (A) and mixed data distribution pattern (B) Rights and permissions Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material

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