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3.4 Post-traumatic stress disorder (PTSD) Gut microbiota alterations in PTSD are increasingly evident in human cohorts, with consistent depletion of SCFA-producing taxa and enrichment of inflammatory pathobionts, while taxa level signatures vary across geography and trauma type (Bajaj et al., 2019

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While we observed a trend of slightly increased intracellular cAMP levels in SGBS cells without GPR146, SVF cells upon GPR146 knockdown exhibited significantly decreased cAMP levels compared to control cells (Fig