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Clinical trials did not include pregnant or breastfeeding women, children, elderly individuals over 65, or those with active malignancy or severe organ dysfunction

Brit J Anaesthesia

Yes, with important qualification

It seems like a variant that should have been weeded out with natural selection

Nutr Cancer 47:126130 Septiani L, Hidayat YM, Mutakin M et al (2016) Serum selenium concentration in cervical cancer patients: Preliminary study and literature review