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The role of vitamin K in chronic aging diseases: inflammation, cardiovascular disease, and osteoarthritis

Accurate and early detection of treatable IEMs through NBS can significantly reduce disease burden and healthcare costs

This approach facilitates personalized interventions such as DGAT1 inhibitors for obese patients exhibiting astrocytic lipid droplet accumulation [278], or NAD + boosters for elderly patients with impaired ketone utilization, as exemplified in the SPAN trial [47, 48, 255]

Early initiation of treatment after the onset of vision loss and a longer treatment duration appears to be associated with better odds of improving or stabilising vision

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