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It is well known that SIRT1 has an anti-aging effect and that its activity can be increased by calorific restriction, which can also reduce cancer risk

Oncogene 34(45):56175625 Hayano M et al (2016) Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

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Type 2 diabetes is a chronic and increasingly prevalent disease in Africa associated with serious complications such as wounds, infections, fatigue, and damage to vital organs [124]