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By contrast, glucose tolerance was only slightly, although significantly, better in N5-WT than in N5-Tr mice and remained close to that observed in BL/6J mice, with a peak blood glucose at ~22 mmol/l in N5-WT vs ~25 mmol/l in N5-Tr mice

Given the strength of the in vitro relationship of GPX4 knockdown and carboplatin sensitivity, we tested the antitumor effects of combining lipid oxidative stress with carboplatin treatment in vivo

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