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HammonsALSummersCMJochemsJAroraJSZhangSBlairIAet alPemetrexed alters folate phenotype and inflammatory profile in EA.hy 926 cells grown under low-folate conditions

While the precise molecular mechanism of TRIM16 action on the p62-Nrf2 system has not been completely defined, TRIM16 expression is associated with increased p62 phosphorylation (Pertel et al., 2011) and other TRIMs (Versteeg Gijs et al., 2013), that phosphorylates p62 (Kehl et al., 2019) and is required for p62 body formation in response to multiple cellular stresses (Kehl et al., 2019)

Jaramillo MC, Briehl MM, Batinic-Haberle I et al (2015) Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells