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We found that upregulated metabolites, such as palmitic acid, isocitric acid, methyl jasmonate, sorbitol, and spermidine, positively correlated with proinflammatory cytokines, such as IL-17 and TNF-, while they negatively correlated with various chemokines, such as IL-8, IL-12, and PDGF-bb ( Figure 6 )

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doi:10.1016/j.ejphar.2015.11.048 Tan SW, Israf Ali DAB, Khaza'ai H, Wong JW, Vidyadaran S