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The autoimmune reactions caused by immune checkpoint inhibitors appear to be dependent on the pathways targeted, as explained in a paper published in Nature Medicine

Elkady WM, Ayoub IM, Abdel-Mottaleb Y, ElShafie MF, Wink M

Transport of l-[ 14 C]cystine and l-[ 14 C]cysteine by subtypes of high affinity glutamate transporters over-expressed in HEK cells

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