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These alterations are responsible for the triggering of MOMP and the stimulation of the intrinsic apoptotic pathway [96]

Because of the small size of IRIS stage groupings, the cats were also separated into an early-stage group (IRIS stages 1 and 2) and a late stage group (IRIS stages 3 and 4), which contained 33 and 28 cats, respectively (Figure 1)

Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)

However, these results have not been reproduced in brain slices or in vivo (reviewed in Papouin and Oliet, 2014)

Agarwal P., Khurana P