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2) BDNF exerts bidirectional regulation of GABAergic transmission by inhibiting GABA signaling in mature GABAergic neurons while enhancing GABA transmission and facilitating LTD in immature GABAergic neurons via the pro-BDNF/p75 neurotrophin receptor (p75(NTR)) pathway (166, 167)

further verification of its mechanism of action requires more systematic and in-depth research

Saify S, Iqbal N, Khan NA (2026) Melatonin and sugar signaling in relation to salt and drought stress tolerance in plants

The coordinated copper ion enables researchers to investigate metal-mediated biochemical processes within controlled laboratory systems while maintaining a defined and reproducible molecular framework