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Thus, in these cells, Cys 2 starvation or system x c inhibitor (such as erastin) cannot induce oxidative stress and cell death 26

(2) Preclinicalclinical disconnect: dosing regimens (e.g., colchicine microneedles) lack human PK/PD validation, while transdermal hydrogels need human skin permeability studies to address species-specific stratum corneum variability

Hgb 9.8 g/dL (down from 11.2 six months ago), ferritin 11 ng/mL, TSAT 9%