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The Importance of Murine Models in Determining In Vivo Pharmacokinetics, Safety, and Efficacy in Antimalarial Drug Discovery

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Modulation of gamma-aminobutyric acid (GABA)related signaling has been observed in preclinical models, a mechanism that may contribute to reduced anxiety-like behaviors and enhanced neural stability (27)

Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and regional aging research contexts, with limited exploratory human data

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