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Last but not least, research was performed on mature rats by injecting lipopolysaccharide to analyze memory impairment

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The insufficient function of the antioxidant system leads to reduced clearance of LPO, and the dynamic imbalance of ROS generation and clearance leads to the accumulation of free radicals, thereby damaging the structure and function of DNA, proteins, and lipids, triggering OS, which is a direct inducer of ferroptosis (Latunde-Dada, 2017

Broadly speaking, 40 years old is the Rubicon, as thats when people tend to see declines in their melatonin levels and their telomere lengths have become significantly shortened.41 42 But 40 is only an approximate milestone