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The effect of HCG in the treatment of obesity by means of the Simeons therapy: A criteria-based meta-analysis

Therefore, abnormal Lab findings, including troponin, brain natriuretic peptide, erythrocyte sedimentation rate, CRP, and cardiac antibodies, when coupled with a concerning clinical presentation and ECG, can be used to make a presumptive diagnosis (207)

This is a concern that applies to all significant weight loss interventions, not just tirzepatide, but it becomes more relevant as the magnitude of weight loss increases