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It has been found that IV supplementation with magnesium can dramatically increase serum levels compared to oral supplementation, and increase the amount that is able to enter into cells

10.1007/s00441-020-03198-6 290 ZengQ.SiuW.LiL.JinY.LiangS.CaoM.et al (2019)

This is followed by bulk intracellular transport along the microtubule shoots, suggesting that these vesicles are probable sources of the newly generated plasma membrane, and membrane tension normalizes within 4 h after injury

"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here

This exclusion is statutory, not just a formulary decision, meaning it cannot be overridden by an appeal or exception request