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Int J Mol Sci 17(6):982 Liu T, Liu Y, Huang Y, Chen J, Yu Z, Chen C, Lai L (2019a) miR-15b induces premature ovarian failure in mice via inhibition of -Klotho expression in ovarian granulosa cells

Jacques MARESCAUX, Professor of Digestive Surgery, President and founder of IRCAD Physiological insulin administration: best favourable outcome for these unstable patients This method of insulin delivery is intended for so-called unstable type 1 diabetic patients who do not respond properly to subcutaneous administration of insulin, which causes large variations in blood sugar levels, leading to severe hypoglycaemia

Addressing these challenges is essential for advancing this promising therapeutic strategy

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In addition, sulforaphane is an HDAC inhibitor used to treat colorectal cancer that can inhibit tumor progression by targeting HDAC1 and HDAC2 [353, 354]