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Mitapivat-induced changes are not limited to reticulocytes, as suggested by the observed significant reduction of erythrophagocytosis (Figure 4B) and the direct effect of mitapivat on splenic macrophages resulting in a proresolving profile

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Part of a multiprotein CoQ metabolon 121 , COQ7 bears a di-iron center that catalyzes penultimate step of ubiquinone biosynthesis 122,123,124,125

Erasmus E, Mienie LJ, de Vries WN, de Wet WJ, Carlsson B, Larsson A: Prenatal analysis in two suspected cases of glutathione synthetase deficiency

[DOI] [PubMed] [Google Scholar] 322.Kordower JH, Chu Y, Hauser RA, Olanow CW, Freeman TB