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This dichotomy may arise from several factors: i) TXNIP-mediated regulation of autophagy is context-dependent, varying across different disease settings (163)

LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice

Recent studies have found that the GlyNAC complex can correct GSH deficiency, counteract oxidative stress, correct type II diabetes, reduce insulin resistance, enhance muscle strength, and improve cognitive function in older adults, suggesting that it has anti-aging effects [28,29,30]

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Bone marrow stromal cell-derived exosomal circular RNA improves diabetic foot ulcer wound healing by activating the nuclear factor erythroid 2-related factor 2 pathway and inhibiting ferroptosis