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WilmerAVan CutsemEAndrioliATackJCoremansGJanssensJ

[152] demonstrated that hyaluronic acid-modified verapamil-loaded CQDs, exhibited enhanced neuronal uptake and neuroprotective efficacy in an in vitro amyloid-induced neurotoxicity model, suggesting transporter-mediated BBB translocation and enhanced intracellular drug distribution [152]

The combination, however, remains unevaluated in controlled studies

Decreased expression of apoptotic Markers, including caspase 3 and caspase 9, along with reduced rates of GC apoptosis in vitro and in vivo, following exosome treatment, supports this observation