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Rahnama P, Javidan AN, Saberi H, Montazeri A, Tavakkoli S, Pakpour AH, et al

Pharmacogenomics J (2017) 17:1629

Figure 2 Excessive intracellular Ca 2+ levels trigger the opening of the mitochondrial permeability transition pore (MPTP), resulting in the loss of mitochondrial membrane potential and hindering ATP production (50)