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A systematic evaluation of peripheral cytokines (e.g., via multiplex Luminex assays) will be conducted in follow-up studies to map gut-derived immune signals to CNS pathology

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doi: 10.1038/s41380-023-02243-4 287 ZhuY.WangX.ZhouX.DingL.LiuD.XuH

Less inflammation, fewer senescent cells and less genomic instability provide a possible explanation for the life-extending effect of GlyNAC

Moreover, treatment with 10 ng/mL of IGF-1 for 10 days was demonstrated to be sufficient to induce tenogenic differentiation of bone marrow MSCs in 3D in vitro culture with significant upregulation of tenocytic markers (SCX, collagen type III, and decorin) (Durgam et al., 2012)