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A total of 398 patients with a mean age of 34.67.2 years participated, in which 92.7% reported moderate or intense endometriosis-associated pelvic pain

Although it does not affect physical health, it can disrupt periorbital esthetics, revealing a tired and aged appearance, thereby affecting the patients quality of life (Citation13)

Other groups of people who have a higher risk include people over age 60, people on certain medications for diabetes, people with Crohns disease, celiac, ulcerative colitis and irritable bowel syndrome and women with a history of infertility or miscarriage

Guerrero JM, Reiter RJ (2002) Melatonin-immune system relationships

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