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(118) found 40 studies published between 2012 and 2020 that were eligible for qualitative review, with a subset of 22 studies that were considered eligible for inclusion in the meta-analysis

10.1210/clinem/dgad053 66 PerksC

These antioxidant effects are thought to be mediated through a dual mechanism: indirectly, by improving systemic metabolism and cardiac energy efficiency (Usman et al., 2024), and more directly, through the inhibition of myocardial NOX2 expression and the activation of endogenous antioxidant pathways such as Nrf2(Preda et al., 2024)