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The direct and weight-independent actions of some new obesity pharmacotherapies in ectopic fat of specific organs may further enhance the potential for tailored treatment choices based on patients complications

Further research is required to optimise support after cessation of WMMs to limit weight regain

The floating church will moor at key regeneration sites for threeto five-year periods, offering services, and developing relationships with growing communities

Standard precautionary principles recommend avoiding use during pregnancy absent compelling medical necessity and informed risk-benefit assessment

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