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Description

& Siegmund, B

Status Not FDA-approved as of June 2026

CD38 ligation plays a direct role in the induction of IL-1beta, IL-6, and IL-10 secretion in resting human monocytes

Doses up to 60mg/kg per day produced no observable toxicity

A 2024 review in Cartilage identified AOD-9604 among key peptides recognized for benefits to bone and joint health, noting its capacity for chondrogenic induction and cartilage regeneration in osteoarthritis models