glutathione synthetase deficiency frequency Metabolism - an overview Frontiers | Case report: A

Previous studies have shown that AMPK inhibition increases intracellular cholesterol synthesis and promotes ROS generation [59], and cells lacking AMPK activity exhibit elevated mtROS levels and undergo premature senescence [60]

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Measurement of glutathione Total glutathione (GSH) was measured spectrophotometrically in the BALF, plasma, and tissues as previously described [17]

These two domains are connected by a short linker sequence of ~10 residues

doi: 10.1007/BF00965326 31 BettendorffLWinsPLesourdM