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For example, vascular damage, cognitive impairment, neurological complications, congenital defects and pregnancy complications A detailed review of these mechanisms is outside the scope of this article

Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects

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Excess ROS can damage all major cellular constituents (DNA, proteins, and lipids) and even lead to cell death, apoptosis, hypertrophy, fibrosis, and contractile dysfunction in the myocardium [8, 11]

Additionally, they protect the skin from oxidative stress and promote collagen synthesis for a smoother and more radiant complexion