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384 This was shown to improve folding of a mechanosensitive channel protein (MscL) in PURE

The causes of this deficiency include poor dietary intake, malabsorption, and pernicious anemia

TABLE 2 Research related to TMAO and human or animal chronic kidney disease models

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Data synthesis The studies varied in terms intervention type, dosage regimens, duration of treatment, study design, and participant characteristics such as disease stage and concurrent medication hence given the substantial heterogeneity, a quantitative meta-analysis was not performed