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While this is often a painless process, in some cases pain, protrusion of the thrombosed hemorrhoids and bleeding can be significant problems

In KRAS/p53 double-mutant pancreatic tumors, targeted degradation of GPX4 selectively induces ferroptosis in cancer cells without affecting immune cell viability and notably enhances the efficacy of immune checkpoint blockade (Li et al., 2023)

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Cytotoxicity evaluation of silymarin nanocrystals The cytotoxicity of silymarin NCs (01000 g/mL) was assessed on a cancerous MDA-MB-231 cell line for 24 h using an MTT assay (Fig